Having heard a noise from outside, Maude left to investigate the commotion. After searching the chicken coop, Maude encountered the monstrous werechicken and was attacked. She later returned to the house and displayed glowing red eyes, right before she transformed into a werechicken herself. Maude consumed Zeke's bowl of popcorn and later continued to terrorize her husband in her form.
Maude, in her villainous werechicken form, was later shown laying an egg, which the Ghostbusters confiscated. The egg hatched and produced a werechicken which infected Egon, who became one himself. At episode's end, both Maude and Egon were cured of the werechicken affliction with chickenbane soup.