Mrs. Fisher (Valerie Dillman) is a villainess from "Savant," the fourth episode of Eleventh Hour (airdate October 30, 2008). She is the wife of neurosurgeon Edward Fisher, and the mother of their four-year-old son, Noah, who was diagnosed with autism.
Mrs. Fisher was also a villainous conspirator with her husband in the abduction of autistic youths, as she would take them and allow Edward to perform unlicensed brain surgeries on them. One of their abducted patients, Scott Butler, ended up dead due to their villainous actions, but even so, the evil Mrs. Fisher continued working with her husband, as she had helped abduct Teresa Kimsey and Cameron Stewart as well. The couple even killed Catherine Bonatelli, who worked with autistic people, by blowing up a building she was in, doing so because she was close to the truth.
The couple's motive was to attempt to cure Noah's autism, and they were officially revealed when they were shown together discussing Catherine's murder, while having Cameron tied up. Dr. Jacob Hood and Agent Rachel Young caught Edward during another of his operations, with the latter ordering him to put down his scalpel. Mrs. Fisher was shown being arrested (after her husband's arrest) for her role in the abductions, as well as the murders of Scott Butler and Catherine Bonatelli.