Cousin Mel (voiced by Michele Lee) is the hidden main antagonist of the 2000 animated Christmas comedy musical adventure fantasy special "Grandma Got Run over by a Reindeer". She is calm, positive, nice, sweet, selfless and motherly. At the end, she is mean, ruthless, taunting, dangerous, bad, murderous and evil. Her goal is to destroy the people in Cityville, kill Jake, Quincy, Santa and Grandma and take over Cityville. Her evil plan is to destroy Jake and his friends.
After her grandparent, Grandma Spankenheimer, refuses to sell her shop to a major corporation, Cousin Mel is outraged, desiring the cash that it would bring. When Grandma suffers the titular accident, Mel usurps ownership of the store and takes measures to ensure that she stays "missing". By the end of the special, she even goes so far as to incriminate Santa Claus himself, but has her plans foiled by her younger cousin Jake. She is then arrested and sent to prison.