An American narcotics agent is murdered in Italy. The head of the department, Jack Goldsmith (William Berger) decides to hire Larry Stanziani (Franco Nero), known as "The Cobra". Larry is a former agent and now a third-rate private detective living in San Francisco. He is sent to Genoa, his hometown, and uses the opportunity to get even with an old enemy. He soon finds out he's facing a relentless organization.
He detects a homosexual drug dealer and murderer named Kandinski, who is also responsible for Larry earning a three-year stay in prison.
Larry gets romantically involved with Brenda, a discotheque DJ. At the end of the film, she turns out to be a villainess, and has been working with the organization. As she pulls out a gun to kill him, she is surprised to be killed herself while in an embrace with Larry.
- Sybil Danning earlier appeard as the evil sorceress Ariadne , in the 1983 Italian adventure film, "Hercules".
- Sybil Danning appeared as Angel in the 1984 action film "Jungle Warriors".
- Sybil Danning appeared as Mary Kruger in the 1984 episode "Visitor's Choice" for the TV series "V".
- Sybil Danning later appeared as Stirba , the main villainess from the 1985 film, "Howling II: Your Sister is a Werewolf".
- Sybil Danning appeared as Warden Sutter in the 1986 film "Refor School Girls".
- Sybil Danning apperead as The Alien Queen in the 1988 film, "The Phantom Empire".
- Sybil Danning later appeared as evil succubus Pamela Dare in the 1989 episode of "Superboy", entitled "Succubus".