Black Nurse is the primary antagonist of the 1992 PC-98 visual novel adventure game "Dengeki Nurse" (電撃ナース) as well as a secondary antagonist in the game's 1994 sequel "Dengeki Nurse 2: More Sexy" (電撃ナース2 ～モアセクシー～).
In the first game, she is the leader of "Black Cross" - a global criminal organization that uses medical technology to do evil.
Black Nurse's new cyborg form...
Black Nurse was thought to have been killed during the final battle with the titular heroine at the end of the first game, but returns in the sequel as an underling to Black Cross's new leader, Jigoku Nurse, with new mechanical anatomy to replace the arm, legs and part of her face that was destroyed. She is the first major villain encountered by Dengeki, who manages to finish Black Nurse off for good during the battle.
Final defeat...
On her throne, commanding her many nurse minions...
After their many failures, she takes matters into her own hands, and hops onto her right-hand, PePe...
Things aren't looking good...
...for Dengeki...
...or her friends.
Ultimately, however, Dengeki proves victorious.
Back with a vengeance as "Black Nurse RX"...