Amy Pond's mother (Leslie Hopps) was a villainess from "The Girl Next Door," episode 7.03 of Supernatural (airdate October 7, 2011) She was the mother of the episode's deuteragonist, Amy Pond, and like her daughter, she was a kitsune, a creature feeding on human brains.
In flashback scenes, Amy's mother entered their house and warned a young Amy that a pair of hunters in an Impala (John and Dean) were after her, unaware that Sam was hiding in the closet. She orders Amy to prepare to move, and while doing so, the villainess caught Sam in the process. Amy protests to killing Sam, but she is struck by her mother, who grows her long claws with intent on feeding on Sam. At that instant, Amy kills her own mother with a knife to save Sam.
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Amy's mother brandishing her long claws